三叉神経 vs. 脊髄神経 論文リスト(Pain Week 2025シンポジウム17)

Aicher, S. A., Hegarty, D. M., & Hermes, S. M. (2014). Corneal pain activates a trigemino-parabrachial pathway in rats. Brain Research, 1550, 18–26. https://doi.org/10.1016/j.brainres.2014.01.002

An, S. Bin, Cho, Y. S., Park, S. K., Kim, Y. S., & Bae, Y. C. (2023). Synaptic connectivity of the TRPV1-positive trigeminal afferents in the rat lateral parabrachial nucleus. Frontiers in Cellular Neuroscience, 17. https://doi.org/10.3389/fncel.2023.1162874

Asquini, G., Devecchi, V., Viscuso, D., Bucci, R., Michelotti, A., Liew, B. X. W., & Falla, D. (2025). An exploratory data-driven approach to classify subgroups of patients with temporomandibular disorders based on pain mechanisms. Journal of Pain, 26. https://doi.org/10.1016/j.jpain.2024.104721

Baker, C. V. H., & Bronner-Fraser, M. (2001). Vertebrate cranial placodes. I. Embryonic induction. In Developmental Biology (Vol. 232, Issue 1, pp. 1–61). https://doi.org/10.1006/dbio.2001.0156

Cavanaugh, D. J., Chesler, A. T., Bráz, J. M., Shah, N. M., Julius, D., & Basbaum, A. I. (2011). Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. Journal of Neuroscience, 31(28), 10119–10127. https://doi.org/10.1523/JNEUROSCI.1299-11.2011

Condon, L. F., Yu, Y., Park, S., Cao, F., Pauli, J. L., Nelson, T. S., & Palmiter, R. D. (2024). Parabrachial Calca neurons drive nociplasticity. Cell Reports, 43(4). https://doi.org/10.1016/j.celrep.2024.114057

Flegel, C., Schöbel, N., Altmüller, J., Becker, C., Tannapfel, A., Hatt, H., & Gisselmann, G. (2015). RNA-Seq analysis of human trigeminal and dorsal root ganglia with a focus on chemoreceptors. PLoS ONE, 10(6). https://doi.org/10.1371/journal.pone.0128951

Kaya, B., Khalil, O., Abssy, S. S., Cioffi, I., & Moayedi, M. (2025). Delineation of the trigeminal-lateral parabrachial-central amygdala tract in humans. Imaging Neuroscience, 3. https://doi.org/10.1162/imag_a_00567

Maric, S., Hasan, M., Pounder, M. L., Graham, B. A., & Browne, T. J. (2025). A Viral Labelling Study of Spinal Trigeminal Nucleus Caudalis Projection Neurons Targeting the Parabrachial Nucleus. Journal of Neurochemistry, 169(3). https://doi.org/10.1111/jnc.70028

Megat, S., Ray, P. R., Tavares-Ferreira, D., Moy, J. K., Sankaranarayanan, I., Wanghzou, A., Lou, T. F., Barragan-Iglesias, P., Campbell, Z. T., Dussor, G., & Price, T. J. (2019). Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling. Journal of Neuroscience, 39(35), 6829–6847. https://doi.org/10.1523/JNEUROSCI.2663-18.2019

Meier, M. L., de Matos, N. M. P., Brügger, M., Ettlin, D. A., Lukic, N., Cheetham, M., Jäncke, L., & Lutz, K. (2014). Equal pain – Unequal fear response: Enhanced susceptibility of tooth pain to fear conditioning. Frontiers in Human Neuroscience, 8(JULY). https://doi.org/10.3389/fnhum.2014.00526

Okuda, T., Uchiyama, S., Sato, N., Sugimura, Y. K., Takahashi, Y., Tsuda, M., & Kato, F. (2025). The posterior-capsular central amygdala (pCeC) showing synaptic coactivation with nociplastic pain-associated parabrachial neurons in mice. IScience, 113001. https://doi.org/10.1016/j.isci.2025.113001

Palmiter, R. D. (2024). Parabrachial neurons promote nociplastic pain. Trends in Neurosciences. https://doi.org/10.1016/j.tins.2024.07.002

Panneton, W. M., & Gan, Q. (2014). Direct reticular projections of trigeminal sensory fibers immunoreactive to CGRP: Potential monosynaptic somatoautonomic projections. Frontiers in Neuroscience, 8 JUN. https://doi.org/10.3389/fnins.2014.00136

Rodriguez, E., Sakurai, K., Xu, J., Chen, Y., Toda, K., Zhao, S., Han, B. X., Ryu, D., Yin, H., Liedtke, W., & Wang, F. (2017). A craniofacial-specific monosynaptic circuit enables heightened affective pain. Nature Neuroscience, 20(12), 1734–1743. https://doi.org/10.1038/s41593-017-0012-1

Schmidt, K., Forkmann, K., Sinke, C., Gratz, M., Bitz, A., & Bingel, U. (2016). The differential effect of trigeminal vs. peripheral pain stimulation on visual processing and memory encoding is influenced by pain-related fear. NeuroImage, 134, 386–395. https://doi.org/10.1016/j.neuroimage.2016.03.026

Sugimoto, M., Takahashi, Y., Sugimura, Y. K., Tokunaga, R., Yajima, M., & Kato, F. (2021). Active role of the central amygdala in widespread mechanical sensitization in rats with facial inflammatory pain. Pain, 162(8), 2273–2286. https://doi.org/10.1097/j.pain.0000000000002224

Svensson, P. (2024). Could painful temporomandibular disorders be nociplastic in nature? A critical review and new proposal. In Acta Odontologica Scandinavica (Vol. 83, pp. 144–150). Medical Journals Sweden AB. https://doi.org/10.2340/aos.v83.40586

Uddin, O., Anderson, M., Smith, J., Masri, R., & Keller, A. (2021). Parabrachial complex processes dura inputs through a direct trigeminal ganglion-to-parabrachial connection. Neurobiology of Pain, 9. https://doi.org/10.1016/j.ynpai.2021.100060

Vermeiren, S., Bellefroid, E. J., & Desiderio, S. (2020). Vertebrate Sensory Ganglia: Common and Divergent Features of the Transcriptional Programs Generating Their Functional Specialization. In Frontiers in Cell and Developmental Biology (Vol. 8). Frontiers Media S.A. https://doi.org/10.3389/fcell.2020.587699

Yajima, M., Sugimoto, M., Sugimura, Y. K., Takahashi, Y., & Kato, F. (2022). Acetaminophen and pregabalin attenuate central sensitization in rodent models of nociplastic widespread pain. Neuropharmacology, 210, 109029. https://doi.org/10.1016/j.neuropharm.2022.109029

Yajima, M., Takahashi, Y., Sugimura, Y. K., & Kato, F. (2023). Pregabalin attenuates long-lasting post-inflammatory nociplastic mechanical sensitization in mice. Neurobiology of Pain, 13, 100131. https://doi.org/10.1016/j.ynpai.2023.100131

Yajima, M., Takahashi, Y., Uezono, Y., & Kato, F. (2025). Mirogabalin and pregabalin alleviate nociplastic sensitization induced by chemogenetic activation of the central amygdala neurons in rodents. Journal of Pharmacological Sciences, 158(2), 77–83. https://doi.org/10.1016/j.jphs.2025.03.004